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LYS228 Pharmacokinetics for Complicated UTI

A Randomized, Controlled, Evaluator-blinded, Multi-center, study to evaluate LYS228 pharmacokinetics, clinical response, safety and tolerability in patients with complicated urinary tract infection

medical-cross
Urinary tract infections
user
All genders
person-wave 18-85
world
Recruiting now
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Overview

Principal Investigator: Dr. Yoav Golan

The purpose of the study is to evaluate whether LYS228 can be developed for the treatment of complicated urinary tract infections

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Deirdre Burke

Study details

Inclusion Criteria
  • Male and female patients 18 to 85 years of age
  • Suspected and/or bacteriologically documented complicated UTI judges by the investigator to be serious (required patient to be hospitalized for treatment with intravenous antibiotics)
Exclusion Criteria
  • Prior antibiotics within the past 72 hours
  • Urine culture resulting with fungal UTI colony count of more than 130 CFU/mL
  • Urine culture resulting in more than 2 different species of microorganisms, or if a gram positive organism is present with >= 105 CFU/mL count.
Study Requirements

Blood draw, Urine samples, clinic visits

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