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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy With Checkpoint Inhibitor Therapy

Breast cancer

All genders

18+

Recruiting now

Department of Medicine, Division of Hematology/Oncology, Cancer Center

Tufts Medical Center

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SOS

Orthopaedic Sports Medicine, Arthoscopy, and Related Surgery Registry Using the Web-Based Surgical Outcomes System

Orthopaedic surgery

All genders

12+

Recruiting now

Department of Orthopaedic Surgery + Rehabilitation Medicine

Tufts Medical Center

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PBCAR0191

Phase 1/2a, Open-label, Dose-escalation, Dose-expansion, Parallel Assignment Study to Evaluate Safety and Clinical Activity of PBCAR0191 in Subjects With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

All genders

18+

Recruiting now

Department of Medicine, Division of Hematology/Oncology, Cancer Center

Tufts Medical Center

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Armata Bacteriophage Study; disArm Study

Phase 1b/2a, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Escalation Study of the Safety, Tolerability, and Efficacy of Intravenous AP-SA02 as an Adjunct to Best Available Antibiotic Therapy Compared to Best Available Antibiotic Therapy Alone for the Treatment of Adults With Bacteremia Due to Staphylococcus aureus.

Bacterial infection, Staphylococcus aureus

All genders

18-100

Recruiting now

Department of Medicine, Division of Geographic Medicine + Infectious Diseases

Tufts Medical Center

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NRG-BN009

Phase III Trial of Salvage Stereotactic Radiosurgery (SRS) or SRS + Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for First or Second Distant Brain Relapse After Upfront SRS With Brain Metastasis Velocity ≥4 Brain Metastases/Year

Brain cancer

All genders

18+

Recruiting now

Department of Medicine, Division of Hematology/Oncology, Cancer Center

Tufts Medical Center

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Schiller Grant BC

Phenotyping Heart Failure Readmission Risk using Wearable Sensors and Machine Learning

Heart failure

All genders

21+

Recruiting now

CardioVascular Center

Tufts Medical Center

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THC-AD

Pilot trial of dronabinol adjunctive treatment of agitation in Alzheimer’s disease (AD) (THC-AD)

Alzheimer's disease, Psychiatric disorders

All genders

60-95

Recruiting now

Department of Psychiatry

Tufts Medical Center

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Pistachio Intake and Macular Pigment; a Randomized Controlled Trial

Pistachios and Neural Macular Pigment; a Randomized Controlled Trial

Eye diseases

All genders

40-70

Recruiting now

Department of Ophthalmology

Tufts Medical Center

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Placental function in early pregnancy

Pregnancy

Female

18-45

Recruiting now

Department of Obstetrics + Gynecology

Tufts Medical Center

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TREO Post Approval Study

Post-Approval Study of the TREO Abdominal Stent-Graft System in Patients with Infrarenal Abdominal Aortic and Aorto-iliac Aneurysms

Abdominal aortic aneurysm, Aortic aneurysm

All genders

18+

Recruiting now

Department of Surgery

Tufts Medical Center

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OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy With Checkpoint Inhibitor Therapy

Orthopaedic Sports Medicine, Arthoscopy, and Related Surgery Registry Using the Web-Based Surgical Outcomes System

Phase 1/2a, Open-label, Dose-escalation, Dose-expansion, Parallel Assignment Study to Evaluate Safety and Clinical Activity of PBCAR0191 in Subjects With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

Phase III Trial of Salvage Stereotactic Radiosurgery (SRS) or SRS + Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for First or Second Distant Brain Relapse After Upfront SRS With Brain Metastasis Velocity ≥4 Brain Metastases/Year

Phenotyping Heart Failure Readmission Risk using Wearable Sensors and Machine Learning

Pilot trial of dronabinol adjunctive treatment of agitation in Alzheimer’s disease (AD) (THC-AD)

Pistachios and Neural Macular Pigment; a Randomized Controlled Trial

Placental function in early pregnancy

Post-Approval Study of the TREO Abdominal Stent-Graft System in Patients with Infrarenal Abdominal Aortic and Aorto-iliac Aneurysms