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TRIOMPHE Study

A Multi-arm, Multi-Center, Non-Randomized, Prospective, Clinical Study to Evaluate the Safety and Effectiveness of the NEXUS^™ Aortic Arch Stent Graft System in Treating Thoracic Aortic Lesions Involving the Aortic Arch: TRIOMPHE Study

Aortic aneurysm, Aortic stenosis

All genders

18+

Recruiting now

Department of Surgery

Tufts Medical Center

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OCEANIC-STROKE

A multicenter, international, randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for the prevention of ischemic stroke in male and female participants aged 18 years and older after an acute non-cardioembolic ischemic stroke or high-risk TIA

Ischemic stroke, Transient ischemic attack

All genders

18+

Recruiting now

Department of Neurology

Tufts Medical Center

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OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer (OPERA-01)

A phase 3 randomized, open-label study of OP-1250 monotherapy vs standard of care for the treatment of ER+, HER2– advanced or metastatic breast cancer following endocrine and CDK 4/6 inhibitor therapy (OPERA-01)

Breast cancer, Locally advanced and metastatic breast cancer

All genders

18+

Recruiting now

Cancer Center

Tufts Medical Center

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SUMMIT MAX

A Prospective, Randomized, Controlled, Interventional Clinical Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical MonoPoint^® Reperfusion System for Aspiration Embolectomy in Acute Ischemic Stroke Patients

Stroke

All genders

18-85

Recruiting now

Department of Neurosurgery

Tufts Medical Center

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AbbVie EAISE

A Randomized, Double-Blind, Placebo-Controlled Proof-of-Concept Study to Assess the Safety and Efficacy of Elezanumab in Acute Ischemic Stroke

Stroke

All genders

30-80

Recruiting now

Department of Neurology

Tufts Medical Center

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PFO-PAS

Amplatzer PFO Occluder Post Approval Study (PFO PAS)

Stroke

All genders

18-60

Recruiting now

Department of Neurology

Tufts Medical Center

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ASPIRE

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

Intracerebral hemorrhage

All genders

18+

Recruiting now

Department of Neurology

Tufts Medical Center

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AbCLO Open Abdomen Study

Assessment of a non-invasive device in the management of Open Abdomen – Pilot Study

Surgery, Trauma

All genders

18-99

Recruiting now

Department of Surgery

Tufts Medical Center

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GORE SYNECOR

Assessment of GORE® SYNECOR Biomaterial in
Focused Patient Populations and Long-Term
Application

Hernia

All genders

18-80

Recruiting now

Department of Surgery

Tufts Medical Center

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ARCADIA

AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenic stroke

Stroke

All genders

45+

Recruiting now

Department of Neurology

Tufts Medical Center

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A Multi-arm, Multi-Center, Non-Randomized, Prospective, Clinical Study to Evaluate the Safety and Effectiveness of the NEXUS^™ Aortic Arch Stent Graft System in Treating Thoracic Aortic Lesions Involving the Aortic Arch: TRIOMPHE Study

A phase 3 randomized, open-label study of OP-1250 monotherapy vs standard of care for the treatment of ER+, HER2– advanced or metastatic breast cancer following endocrine and CDK 4/6 inhibitor therapy (OPERA-01)

A Prospective, Randomized, Controlled, Interventional Clinical Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical MonoPoint^® Reperfusion System for Aspiration Embolectomy in Acute Ischemic Stroke Patients

A Randomized, Double-Blind, Placebo-Controlled Proof-of-Concept Study to Assess the Safety and Efficacy of Elezanumab in Acute Ischemic Stroke

Amplatzer PFO Occluder Post Approval Study (PFO PAS)

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

Assessment of a non-invasive device in the management of Open Abdomen – Pilot Study

Assessment of GORE® SYNECOR Biomaterial in
Focused Patient Populations and Long-Term
Application

AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenic stroke