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Cutaneous Lupus Erythematosus and/or Chronic Cutaneous Lupus Erythematosus

2-Part Seamless Part A (Phase 2)/Part B (Phase 3) Randomized,
Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the
Efficacy and Safety of BIIB059 in Participants with Active Subacute
Cutaneous Lupus Erythematosus and/or Chronic Cutaneous Lupus
Erythematosus with or without Systemic Manifestations and Refractory
and/or Intolerant to Antimalarial Therapy (AMETHYST)

Cutaneous disorders

All genders

18+

Recruiting now

Department of Dermatology

Tufts Medical Center

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Psoriasis

A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled and Deucravacitinib Active Comparator-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Psoriasis

All genders

18+

Recruiting now

Department of Dermatology

Tufts Medical Center

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Organogenesis Knee OA

A Phase 3 Prospective, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Amniotic Suspension Allograft (ASA) in Patients with Osteoarthritis of the Knee

Osteoarthritis

All genders

18+

Recruiting now

Department of Medicine, Division of Rheumatology

Tufts Medical Center

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Atopic Dermatitis (Eczema)

A Phase 3, randomized, double-blind, placebo-controlled, parallel-group, 3-arm, multinational, multicenter study to evaluate the efficacy and safety of amlitelimab monotherapy by subcutaneous injection in participants aged 12 years and
older with moderate-to-severe atopic dermatitis (eczema).

Atopic dermatitis

All genders

12-17

Recruiting now

Department of Dermatology

Tufts Medical Center

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TAP Block and minimally invasive hysterectomy for pain control

A randomized, controlled, observer-blinded pilot trial of laparoscopic large volume, multisite transversus abdominal plane (TAP) block with liposomal bupivacaine in patients undergoing minimally invasive hysterectomy for endometrial cancer

Uterine cancer

Female

18-80

Recruiting now

Department of Obstetrics + Gynecology

Tufts Medical Center

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RA-PROPR

A Real-World Comparative Effectiveness Trial of Treatment Strategies in Patients with Rheumatoid Arthritis

Rheumatoid arthritis

All genders

18+

Recruiting now

Department of Medicine, Division of Rheumatology

Tufts Medical Center

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Application of N-of-1 Clinical Trial Design in Rhematoid Arthritis

Application of the N-of-1 Trial Design Paradigm
Rheumatoid Arthritis Protocol

Rheumatoid arthritis

All genders

18-65

Recruiting now

Division of General Internal Medicine , Division of Rheumatology

Tufts Medical Center

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Tai Chi and Microbiota in Osteoarthritis Study

Gut Microbiota and Osteoarthritis Study

Osteoarthritis

All genders

55+

Recruiting now

Department of Medicine, Division of Rheumatology

Tufts Medical Center

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Multi-spectral imaging

Label-free, multi-scale imaging for improved detection of ovarian cancer metastases

Ovarian cancer

Female

18-99

Recruiting now

Department of Medicine, Division of Hematology/Oncology, Cancer Center

Tufts Medical Center

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Non- Invasive, Label-free Detection of Cervical Pre-Cancers In vivo

Non-Invasive, Label-free Detection of Cervical Pre-Cancers In vivo

Cervical cancer

All genders

18-100

Recruiting now

Department of Obstetrics + Gynecology

Tufts Medical Center

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A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled and Deucravacitinib Active Comparator-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

A Phase 3 Prospective, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Amniotic Suspension Allograft (ASA) in Patients with Osteoarthritis of the Knee

A Phase 3, randomized, double-blind, placebo-controlled, parallel-group, 3-arm, multinational, multicenter study to evaluate the efficacy and safety of amlitelimab monotherapy by subcutaneous injection in participants aged 12 years and
older with moderate-to-severe atopic dermatitis (eczema).

A randomized, controlled, observer-blinded pilot trial of laparoscopic large volume, multisite transversus abdominal plane (TAP) block with liposomal bupivacaine in patients undergoing minimally invasive hysterectomy for endometrial cancer

A Real-World Comparative Effectiveness Trial of Treatment Strategies in Patients with Rheumatoid Arthritis

Application of the N-of-1 Trial Design Paradigm
Rheumatoid Arthritis Protocol

Gut Microbiota and Osteoarthritis Study

Label-free, multi-scale imaging for improved detection of ovarian cancer metastases

Non-Invasive, Label-free Detection of Cervical Pre-Cancers In vivo