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Evaluation of BE1116 (4F-PCC) in patients with traumatic injury and confirmed or suspected acute major bleeding to improve survival

A Prospective, Multicenter, Randomized, Double-Blind, Placebo-Controlled,Large Simple Trial Evaluating the Use of BE1116 (4-Factor Prothrombin Complex Concentrate [Kcentra^® / Beriplex^®]) to Improve Survival in Patients with Traumatic Injury and Confirmed or Suspected Acute Major Bleeding Predicted to Receive a Large Volume Blood Product Transfusion

Trauma

All genders

15+

Recruiting now

Department of Surgery, Division of Trauma

Tufts Medical Center

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Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

EA3132 - Phase II Randomized Trial of Radiotherapy with or without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) with TP53 Sequencing

Squamous cell carcinoma

All genders

18+

Recruiting now

Department of Medicine, Division of Hematology/Oncology, Cancer Center

Tufts Medical Center

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ESS Validation Surgery

Validation of Elastic Scattering Spectroscopy for Intra-operative Margin Guidance during Oral Cancer Resection

Mouth disorders

All genders

18+

Recruiting now

Department of Otolaryngology – Head + Neck Surgery

Tufts Medical Center

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EA3132 - Phase II Randomized Trial of Radiotherapy with or without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) with TP53 Sequencing

Validation of Elastic Scattering Spectroscopy for Intra-operative Margin Guidance during Oral Cancer Resection