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Showing 1 - 10 out of 25

DEFENDO Long-Term Follow-Up Study

A long-term extension study to evaluate the safety and efficacy of OXERVATE 0.002% (20 mcg/mL) cenegermin-bkbj ophthalmic solution in patients with Stage 1 Neurotrophic Keratitis who enrolled in the DEFENDO Study

Neurotrophic keratitis

All genders

18+

Recruiting now

Department of Ophthalmology

Tufts Medical Center

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TRIOMPHE Study

A Multi-arm, Multi-Center, Non-Randomized, Prospective, Clinical Study to Evaluate the Safety and Effectiveness of the NEXUS^™ Aortic Arch Stent Graft System in Treating Thoracic Aortic Lesions Involving the Aortic Arch: TRIOMPHE Study

Aortic aneurysm, Aortic stenosis

All genders

18+

Recruiting now

Department of Surgery

Tufts Medical Center

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Organogenesis Knee OA

A Phase 3 Prospective, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Amniotic Suspension Allograft (ASA) in Patients with Osteoarthritis of the Knee

Osteoarthritis

All genders

18+

Recruiting now

Department of Medicine, Division of Rheumatology

Tufts Medical Center

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SEER-2

A Phase 3, Multi-Center, Randomized, Parallel, Double Masked, Placebo-Controlled Clinical Study to Assess the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of Neurotrophic Keratopathy (SEER-2)

Neurotrophic keratitis

All genders

18+

Recruiting now

Department of Ophthalmology

Tufts Medical Center

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POETYK SjS-1

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults with Active Sjögren’s Syndrome (POETYK SjS-1)

Sjogren's syndrome

All genders

18+

Recruiting now

Department of Ophthalmology

Tufts Medical Center

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BALATON

A Phase III, Multicenter, Randomized, Double-Masked, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of Faricimab in Patients with Macular Edema Secondary to Branch Retinal Vein Occlusion

Macular degeneration

All genders

18+

Recruiting now

Department of Ophthalmology

Tufts Medical Center

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Belvedere

A Phase IV, Multicenter, Open-label, Single-Arm study of the response to treatment after transition to the port delivery system with Ranibizumab (Susvimotom [Ranibizumab injection]) in patients with neovascular age-related macular degeneration previously treated with intravitreal agents other than Ranibizumab.

Macular degeneration

All genders

50+

Recruiting now

Department of Ophthalmology

Tufts Medical Center

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RA-PROPR

A Real-World Comparative Effectiveness Trial of Treatment Strategies in Patients with Rheumatoid Arthritis

Rheumatoid arthritis

All genders

18+

Recruiting now

Department of Medicine, Division of Rheumatology

Tufts Medical Center

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KPI-012-C-001

A Study to Evaluate the Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants with Persistent Corneal Epithelial Defect (PCED)

Corneal disorders

All genders

18+

Recruiting now

Department of Ophthalmology

Tufts Medical Center

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Application of N-of-1 Clinical Trial Design in Rhematoid Arthritis

Application of the N-of-1 Trial Design Paradigm
Rheumatoid Arthritis Protocol

Rheumatoid arthritis

All genders

18-65

Recruiting now

Division of General Internal Medicine , Division of Rheumatology

Tufts Medical Center

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A long-term extension study to evaluate the safety and efficacy of OXERVATE 0.002% (20 mcg/mL) cenegermin-bkbj ophthalmic solution in patients with Stage 1 Neurotrophic Keratitis who enrolled in the DEFENDO Study

A Multi-arm, Multi-Center, Non-Randomized, Prospective, Clinical Study to Evaluate the Safety and Effectiveness of the NEXUS^™ Aortic Arch Stent Graft System in Treating Thoracic Aortic Lesions Involving the Aortic Arch: TRIOMPHE Study

A Phase 3 Prospective, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Amniotic Suspension Allograft (ASA) in Patients with Osteoarthritis of the Knee

A Phase 3, Multi-Center, Randomized, Parallel, Double Masked, Placebo-Controlled Clinical Study to Assess the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of Neurotrophic Keratopathy (SEER-2)

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults with Active Sjögren’s Syndrome (POETYK SjS-1)

A Phase III, Multicenter, Randomized, Double-Masked, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of Faricimab in Patients with Macular Edema Secondary to Branch Retinal Vein Occlusion

A Real-World Comparative Effectiveness Trial of Treatment Strategies in Patients with Rheumatoid Arthritis

A Study to Evaluate the Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants with Persistent Corneal Epithelial Defect (PCED)

Application of the N-of-1 Trial Design Paradigm
Rheumatoid Arthritis Protocol