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The Hu lab studies angiogenesis in cancers and in neurodegenerative diseases.
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In the Covic laboratory, we study a novel class of cell surface proteins known as protease-activated receptors.
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The members of the Division of Colon and Rectal Surgery have a wide number of research interests including complications of ostomies, inflammatory bowel disease, pathogenesis of colorectal and anal cancer and treatment of early rectal cancer.
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Rebecca Perkins, MD, MSc, is a Professor of Obstetrics and Gynecology at Tufts University School of Medicine and an Attending Gynecologist at Tufts Medical Center.
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The Comenzo laboratory is focused on the investigation of clonal plasma cell diseases  with emphases on multiple myeloma and systemic light-chain (AL) amyloidosis. Our core projects are assessing the risk of progressing to AL from smoldering multiple myeloma, analyzing the cytologic and molecular changes in normal tissue in response to immunoglobulin light chains and deposits of amyloid, and the development of novel therapeutics that target and clear pathologic light chains.
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The Buchsbaum Laboratory focuses on studying signal transduction pathways underlying cancer cell growth and metastasis. In particular, we are interested in pathways involving the Rac protein, a member of the Ras superfamily that is a central player in multiple signaling pathways affecting malignant cell behavior.
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The Miaofen Hu laboratory is studying the role of CDK6 in Notch-mediated stem cell transformation and leukemogenesis.
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The MCRI sponsors Multidisciplinary Research Groups that foster collaboration among clinical, translational and basic scientists including MCRI faculty and investigators across Tufts Medicine and Tufts University. These groups include the Cardio-Oncology Research Group, the Cardio-Renal Research Group, the Vasculo-Neuro Research Group, the Women’s Cardiovascular Health Research Group, and the Wound Healing Research Group.
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Our faculty actively participates in clinical and basic sciences research on urological oncology, benign prostate hyperplasia (BHP) and minimally invasive surgical procedures. Basic laboratory research is focused on prostate cancer and BPH.
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