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Our neurosurgeons extend hope and healing to people living with nervous system conditions like brain tumors, epilepsy and aneurysms. From spine surgery to operating on the tiny blood vessels that pump blood to the brain (cerebrovascular surgery), our neurosurgeons always have your well-being top of mind. ...
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This trial has two parts. Part A, an initial non-randomized Safety Run-In Phase to confirm the safety and tolerability at the selected dose range level of BNT113 in combination with pembrolizumab. Part B, the Randomized Phase of BNT113 in combination with pembrolizumab versus pembrolizumab monotherapy to generate pivotal efficacy and safety data in the first line setting in patients with unresectable recurrent or metastatic HPV16+ HNSCC expressing PD-L1 with CPS ≥1. Randomization will be stratified by PDL1 CPS <20 vs PD-L1 CPS ≥20, and prior chemotherapy (yes vs no).
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In the Covic laboratory, we study a novel class of cell surface proteins known as protease-activated receptors.
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The members of the Division of Colon and Rectal Surgery have a wide number of research interests including complications of ostomies, inflammatory bowel disease, pathogenesis of colorectal and anal cancer and treatment of early rectal cancer.
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Working closely together, our clinical teams care for patients from birth through their late teenage years.  At Tufts Medical Center in Boston, we strive to keep the children and adolescents of our community healthy by providing routine primary care as well as emergency care and day surgery. 
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The MelroseWakefield Hospital Men's Health Clinic promotes sexual health by providing screening and treatment of sexually transmitted infections, anal dysplasia as well as preventive services, including HIV prophylaxis (PrEP, PEP, Doxy-PEP).
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Hospital
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Originally founded in 1893, we are a 234-bed general hospital offering a wide range of services, including expert cardiac care, 24-hour emergency care, wound care management and maternity services with an on-site Level II Special Care Nursery. We are the only hospital in the area offering an emergency cardiac catheterization lab, a life-saving procedure to open blocked arteries and limit heart damage. We are supported by over 700 affiliated physicians and have access to advanced specialty care with our clinical affiliation with Tufts Medical Center. 
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Rebecca Perkins, MD, MSc, is a Professor of Obstetrics and Gynecology at Tufts University School of Medicine and an Attending Gynecologist at Tufts Medical Center.
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The Comenzo laboratory is focused on the investigation of clonal plasma cell diseases  with emphases on multiple myeloma and systemic light-chain (AL) amyloidosis. Our core projects are assessing the risk of progressing to AL from smoldering multiple myeloma, analyzing the cytologic and molecular changes in normal tissue in response to immunoglobulin light chains and deposits of amyloid, and the development of novel therapeutics that target and clear pathologic light chains.
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The Buchsbaum Laboratory focuses on studying signal transduction pathways underlying cancer cell growth and metastasis. In particular, we are interested in pathways involving the Rac protein, a member of the Ras superfamily that is a central player in multiple signaling pathways affecting malignant cell behavior.
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The Miaofen Hu laboratory is studying the role of CDK6 in Notch-mediated stem cell transformation and leukemogenesis.
Service
Speech-language pathology evaluates and treats people who have difficulty speaking, communicating or swallowing. We’re dedicated to helping people of all ages overcome speech, language, cognitive, swallowing and other communication disorders to find their authentic voice. ...
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The MCRI sponsors Multidisciplinary Research Groups that foster collaboration among clinical, translational and basic scientists including MCRI faculty and investigators across Tufts Medicine and Tufts University. These groups include the Cardio-Oncology Research Group, the Cardio-Renal Research Group, the Vasculo-Neuro Research Group, the Women’s Cardiovascular Health Research Group, and the Wound Healing Research Group.