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Since January 2018, the CardioVascular Center has published numerous reports in peer-reviewed journals. These are the highlighted high-impact manuscripts from this quarter.
Press Releases
January 25, 2021
Internationally esteemed clinician and health equity researcher, Karen Freund, MD, MPH has been named Physician-in-Chief and Chair of the Department of Medicine at Tufts Medical Center, effective February 1. She will also assume the role of Chair of the Department of Medicine at Tufts University School of Medicine, both effective February 1.
department
The Department of Medicine helps us stand tall as one of the country’s leading health systems. While we take great pride in celebrating our department’s accomplishments, it’s our commitment to training tomorrow's primary care doctors, hospitalists and subspecialists that moves the needle of clinical care forward.
Articles
December 20, 2019
Anxiety can be normal and a disorder. Learn from Tufts Medical Center expert on what anxiety is and tips on managing it.
Announcements
August 10, 2021
Every day we have the privilege of helping people heal and become their best, healthiest selves. These individuals turn to us when they are most vulnerable and trust that we will care for them safely. To serve them well, we also must be our healthiest and best selves and the best way to be healthy amidst this ongoing pandemic is vaccination.
clinical trial
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This is a prospective, multi-center clinical study to validate the effectiveness of the Boppli Blood Pressure Monitor as compared to an invasive arterial reference. This study will evaluate the accuracy and precision of the Boppli system for continuous blood pressure monitoring by comparing SBP, DBP, and MAP against the reference methodology in pediatric and neonatal populations.
Patient Stories
January 30, 2020
Mac and his team at Tufts MC refused to let cardiomyopathy take his life, so they did all they could to get him to a heart transplant.
clinical trial
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Gore has developed and manufactures the GORE® SYNECOR Intraperitoneal Biomaterial device (GORE® SYNECOR IP Device) to offer clinicians a mesh material intended for the repair of ventral/incisional hernias that may require the addition of a nonabsorbable reinforcing or bridging material. The primary study objective is to assess SYNECOR Biomaterial performance on incisional hernia patients over an extended amount of time through multiple methods. The secondary study objective is to conduct configuration-specific assessments to address areas of medical interest.
clinical trial
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This study aims to learn more about the investigational drug, ASTX727, and another drug, venetoclax, when given in combination. It also aims to evaluate potential pharmocokinetics (PK) interactions for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults who are age 75 years or older, or who have comorbidities that preclude use of intensive induction chemotherapy.

The primary purpose of the study is to rule out drug-drug interactions between ASTX727 and venetoclax combination therapy.
department
The understanding of cancer is growing every day and our clinicians are making a significant impact on how the world researches, teaches and delivers care to improve quality and quantity of life.
Announcements
November 7, 2022
Tufts Medical Center patient, triathlete overcomes brain aneurysm to complete Ironman competition.
Articles
August 14, 2024
Tufts Medical Center’s Andre J. Witkin, MD, Professor of Ophthalmology, board-certified ophthalmologist and vitreoretinal specialist and surgeon, shares how to reduce your risk of developing diabetic retinopathy (DR).
clinical trial
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This is a single center prospective cohort study. The cohort (interventional) patients will receive the study intervention (ABCLO). The control group retrospective patients that were previously managed at the same center, regardless of the technique or the device used to close the OA.
department
The Department of Ophthalmology and New England Eye Center makes healthier possible with expert diagnosis and treatment of eye diseases and visual problems. Beyond our clinical care, we’re leading the way to the future of ophthalmic care through training and education programs, eye research and ophthalmic technology development.
clinical trial
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The primary goal of this study is to improve our understanding of changes in skeletal muscle mass in the arms and the legs during a hospitalization for advanced HF. We plan to measure muscle thickness with an ultrasound machine in two locations on the body (the outer thigh and the upper arm muscle, of the dominant side) from the time a patient is first admitted to the ICU with HF as well as before and after any surgical HF therapies.
Articles
October 19, 2021
From screening mammograms to second opinions and advanced breast surgery, we understand the unique needs and opportunities for managing breast health and disease. Through our clinical collaboration with Tufts Medical Center Cancer Center in Stoneham, we bring a high level of breast care services locally.
clinical trial
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This is a clinical study that explores the effects of Tai Chi or Wellness Education on the gut bacteria of patients with Osteoarthritis. Our intervention is aimed at decreasing pain and improving quality of life for osteoarthritis patients.

To measure bacterial changes, participants stool samples will be collected and analyzed.These results will help determine mechanisms between bacteria, pain and behavioral pathways as well as progress future research to the potential disease-modifying role of mind-body approaches.