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The Comenzo laboratory is focused on the investigation of clonal plasma cell diseases  with emphases on multiple myeloma and systemic light-chain (AL) amyloidosis. Our core projects are assessing the risk of progressing to AL from smoldering multiple myeloma, analyzing the cytologic and molecular changes in normal tissue in response to immunoglobulin light chains and deposits of amyloid, and the development of novel therapeutics that target and clear pathologic light chains.

Since January 2018, the CardioVascular Center has published numerous reports in peer-reviewed journals. These are the highlighted high-impact manuscripts from this quarter.