Clinical + Translational Science Institute

Tufts Clinical and Translational Science Institute (CTSI) was established in August 2008 as part of a national consortium to transform how clinical and translational research is conducted throughout the country.

Our mission is to identify, stimulate and expedite innovative clinical and translational research to improve the public’s health.

Led by our Dean and the Principal Investigator, Harry P. Selker, MD, MSPH, our leadership team is comprised of world-renowned experts in clinical research, comparative effectiveness research, community engagement and research collaboration.

We work closely with 39 partner institutions, including all of the schools of Tufts University, its affiliated hospitals across Massachusetts and Maine, participating universities, community organizations and non-profit and for-profit organizations.

 Research associate and staff nurse working in laboratory in the Clinical and Translational Research Center.
We are transforming how clinical and translational research is conducted.
Our website

Services + Facilities

The Tufts Clinical and Translational Science Institute (CTSI) is responsible for CTRC business management, including operations, personnel, research administration, facilities and finance.

Surrogate Endpoints

Proteinuria has been established as a marker of kidney damage in experimental studies and clinicians consider an early reduction in albuminuria as indicative of a favorable response to treatment.
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Surrogate Endpoints

Studies

ckd epi presentation
New studies are being added to CKD-EPI on a rolling basis.

GFR Estimation

Lesley Inker, MD, received the Clinical Research Forum Distinguished Clinical Research Achievement Award for the CFD-EPI's research on new creatine-and cystatin c-based equations to estimate GFR without race. Dr. Inker is a recognized leader in the field of kidney function evaluation. She has authored more than 100 publications on kidney health.

 Leslie A. Inker, MD, MS, Director, Quality Improvement, Division of Nephology working at her computer in office.
Lesley Inker, MD, received the Clinical Research Forum Distinguished Clinical Research Achievement Award in 2022. The award recognizes CKD-EPI's research on new creatine and cystatin c-based equations to estimate GFR without race. Dr. Inker is a recognized leader in the field of kidney function evaluation. She has authored more than 100 publications on kidney health.