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This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard endocrine therapy in patients with ER+/HER2 - early breast cancer who completed definitive locoregional therapy (with or without chemotherapy) and standard adjuvant endocrine therapy (ET) for at least 2 years and up to 5 years. The eligible patients must have intermediate or high risk of recurrence, as defined by specified clinical and biologic criteria.
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Did you know Tufts Medical Center is the oldest hospital in Boston? Tufts Medical Center was established as the Boston Dispensary and was the first operating medical center in New England- and the third in the United States. It was commissioned by Paul Revere.
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No matter where you call home, our home care team will meet you where you are and deliver care that puts comfort, quality of life and independence first. From helping with everyday chores to ongoing treatment for chronic illness, our visiting nurses and care team will be there for you every step of the way. ...
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Our pulmonologists have expertise in diagnosing and treating lung conditions common in patients of Asian descent. What truly sets us apart is that we are dedicated to providing culturally-sensitive and expert care. With an interpreter by your side throughout your visit, you can rest assured that you'll receive the personalized care and support you deserve throughout your treatment. ...
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Monoclonal gammopathy of renal significance (MGRS) is a plasma cell disease where a person has an abnormal protein in their blood. This protein can cause kidney damage and lead to kidney failure when left untreated. ...
Medical clinic
No matter your child's age, we're dedicated to providing the best possible care for their skin. We specialize in diagnosing and treating skin conditions that affect young people the most, from birthmarks to cystic acne to even stubborn skin infections. ...
Medical clinic
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When Lowell General Hospital was founded in 1891, we opened our doors to the community as a welcoming place where patients always come first. That mission is at the heart of how we provide healthcare to all who come through our doors today.
About Lowell General Hospital
clinical trial
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The purpose of this study is to determine whether treatment with OP-1250 as a monotherapy will result in improvement of progression-free survival (PFS) and overall survival (OS) compared to SOC ET and assess the safety of treatment with OP-1250 in participants with ER+, HER2– advanced or MBC with and without estrogen receptor 1 gene (ESR1) activating mutation(-s) whose disease has relapsed or progressed on 1 or 2 prior lines of SOC ET, including a cyclin-dependent kinase (CDK) 4/6 inhibitor.
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Our geriatric rehabilitation specialists are dedicated to helping older adults overcome medical and age-related conditions so that they may rediscover their strength, mobility, balance and comfort. ...
Medical clinic
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Located on the 4th floor of 41 Montvale Avenue in Stoneham, the Breast Health Center offers patients access to the latest technological advances in the prevention, early detection, diagnosis and treatment of breast disease.

We offer expert care in a comfortable, patient-centered environment with on-site diagnostic mammography, pelvic floor rehabilitation and lymphedema physical therapy.
Medical clinic
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We’re here to take care of your heart with kindness and the most advanced treatments available. Did you know nearly half of all Americans have some form of heart disease? That’s why we’re ready to help you stay healthy with prevention tips or give you a fresh start through life-changing treatments like heart transplants. ...
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No one believes in our mission more than those on the front lines of care — our employees. Whether you work in accounts payable, at High Pointe House, as part of a care team, in urgent care or in a research lab, supporting our programs can be as easy as an automatic payroll deduction.
Employee Giving
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Your donation to Lowell General Hospital ensures patients receive exceptional care, from routine appointments and health screenings to surgeries and treatments.
Give to Lowell General Hospital