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HIP ATTACK-2 is a multi-center, international, randomized controlled trial to determine whether accelerated surgery for hip fracture in patients with acute myocardial injury is superior to standard care in reducing death at 90 days after randomization. Other outcomes include; inability to walk 3 meters independently, time to standing and weight-bearing, delirium, length of stay, pain, and quality of life.

This study will describe and compare the rates of asthma exacerbations observed between 12-month pre-switch and 12-month post-switch periods among participants switching to AIRSUPRA. Other outcome measures included in this study are asthma-related oral corticosteroid (OCS) use, and asthma exacerbation-related healthcare resource utilization (HCRU), healthcare cost, and patient reported outcomes (PROs).

This is a Phase 3, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ravulizumab compared with placebo in participants with primary IgAN on optimal treatment with renin-angiotensin system (RAS) blockade using angiotensin converting enzyme inhibitors (ACEIs) and/or angiotensin II receptor blockers (ARBs) who are at risk of progressing to end stage kidney disease (ESKD).

This study will evaluate infant vision health based on the history of prenatal drug exposure. Data from this study will be used to create a new process which will include vision health as part of the discharge planning for infants with prenatal drug exposure admitted to Tufts Medicine Pediatrics.

The goal of this study is to develop a faster, safer, and more accurate method for determining if a newborn has an infection. This study involves analyzing saliva for markers of infection and inflammation known as cytokines. We will analyze infant’s saliva repeatedly for inflammatory biomarkers within the first 36 hours of their standard of care treatment. We hypothesize that levels of these cytokines will more quickly predict which babies are truly infected and which babies are not compared to the blood test currently being used.

The aims of the study are: